FOR US HEALTHCARE PROFESSIONALS FOR PATIENTS

Important Safety Information

Do not take LAMPIT tablets if you are allergic to nifurtimox, or any of the ingredients in LAMPIT or plan to drink alcohol during treatment with LAMPIT.  Continue reading below

Important Safety Information

Do not take LAMPIT tablets if you are allergic to nifurtimox, or any of the ingredients in LAMPIT or plan to drink alcohol during treatment with LAMPIT. Continue reading below

LAMPIT® can help children in their fight against Chagas disease

LAMPIT® can help children in their fight against Chagas disease

LAMPIT is the only FDA-approved treatment for Chagas disease caused by the parasite Trypanosoma cruzi for children of all ages, from birth to younger than 18 years, who weigh at least 5.5 pounds (2.5 kg)

The medicine comes in tablet form and is available in 2 dosage strengths: 30 mg and 120 mg.

Lampit packaging

What is LAMPIT?

LAMPIT® is a prescription medicine used to treat Chagas disease caused by the parasite Trypanosoma cruzi in children less than 18 years of age weighing at least 5.5 pounds (2.5 kg). It is not known if LAMPIT is safe and effective in children weighing less than 5.5 pounds (2.5 kg).

How to take LAMPIT

LAMPIT is taken 3 times a day with food, and the recommended treatment duration is 60 days. It is important to take LAMPIT exactly as your healthcare provider tells you and to finish all of the medication to prevent recurrence of the infection. The dosing is based on how much the patient weighs. 

 

Your healthcare provider may need to change your dose of LAMPIT during treatment as needed. Use it exactly as prescribed. LAMPIT 30 mg tablets and 120 mg tablets have a scored line on one side and can be taken whole or broken along this line. 

 

If you miss a dose of LAMPIT, take the missed dose as soon as possible with food. If it is within 3 hours of the next scheduled dose, skip the missed dose and take the next dose at your regular time. Do not take 2 doses to make up for a missed dose. 

 

There are some important things to remember when taking LAMPIT: 

  • Do not take more LAMPIT than prescribed by your healthcare provider
  • Take LAMPIT with food
  • Split LAMPIT tablets by hand. Do not split LAMPIT tablets using a tablet splitting device. See the instructions below for splitting tablets by hand
  • If you cannot swallow LAMPIT tablets or you are giving LAMPIT to a child who cannot swallow the tablets, you can dissolve the tablet in water and give the mixture with food. See the instructions below for preparing a tablet and water mixture (slurry)

HOW TO SPLIT LAMPIT TABLETS BY HAND

1

Step 1: To split the tablet, place the tablet on a flat surface with the scored line facing up.

Lampit tablet icon

2

Step 2: With the tablet still on the flat surface, apply enough pressure down on the center of the tablet with your index finger to split it in half along the scored line.

Finger on Lampit tablet

3

Step 3: LAMPIT tablets can
be split in half along the scored line.

Finger splitting Lampit tablet

4

Step 4: Only use a tablet that has been broken at the scored line.

Split Lampit tablet

Do not split LAMPIT tablets in any other way.

PREPARING A TABLET AND WATER MIXTURE (SLURRY)

For people who are not able to swallow whole tablets or half tablets, LAMPIT can be mixed in water. 

1

Step 1: Place approximately one-half teaspoonful (2.5 mL) of water into a spoon.

Water in spoon icon

2

Step 2: Place the prescribed dose into the water.

Lampit tablet and water in spoon icon

3

Step 3: Allow the tablet to dissolve in the water. This should take less than 30 seconds.

Lampit tablet dissolving in water in spoon icon

4

Step 4: A tablet and water mixture (slurry) will form.

Lampit slurry mixture icon

Give the tablet and water mixture (slurry) right away with food. Do not mix more than the prescribed dose.

If you miss a dose: Take the missed dose as soon as possible with food. If it is within 3 hours of the next scheduled dose, skip the missed dose and take the next dose at the regular time. Never take 2 doses to make up for a missed dose.

 

LAMPIT and pregnancy

Before taking LAMPIT, tell your healthcare provider if you are pregnant, plan to become pregnant, or think you may be pregnant. LAMPIT can harm your unborn baby.

 

For females who are able to become pregnant:

  • Your healthcare provider should do a pregnancy test before you start taking LAMPIT to make sure that you are not pregnant
  • You should use effective forms of birth control during treatment with LAMPIT and for 6 months after your last dose of LAMPIT. Talk to your healthcare provider about what forms of birth control may be right for you
  • Call your healthcare provider right away if you become pregnant or think you are pregnant during treatment with LAMPIT

 

For males:

  • LAMPIT may cause fertility problems in males. This may affect your ability to father a child. Talk to your healthcare provider if you have concerns about fertility
  • You should use a condom with female partners who are able to become pregnant, during treatment with LAMPIT and for 3 months after your last dose of LAMPIT

 

Storing LAMPIT

  • Store LAMPIT at room temperature between 68°F to 77°F (20°C to 25°C)
  • Keep LAMPIT in the bottle that it comes in with the child-resistant cap on the bottle. Do not remove the packet that helps to keep your medicine dry (desiccant)
  • Keep the bottle tightly closed and protect from moisture

 

Keep LAMPIT and all medicines out of the reach of children.

Most common side effects

The most common side effects of LAMPIT include:  

  • Vomiting

  • Abdominal pain

  • Headache

  • Decreased appetite

  • Nausea
  • Fever

  • Rash

These are not all of the possible side effects of LAMPIT. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

 

See the LAMPIT (nifurtimox) tablets Full Prescribing Information, which includes Patient Information and Instructions for Use.

What is LAMPIT?

LAMPIT® is a prescription medicine used to treat Chagas disease caused by the parasite Trypanosoma cruzi in children less than 18 years of age weighing at least 5.5 pounds (2.5 kg). It is not known if LAMPIT is safe and effective in children weighing less than 5.5 pounds (2.5 kg).

 

 

Important Safety Information

Do not take LAMPIT tablets if you:

  • Are allergic to nifurtimox, or any of the ingredients in LAMPIT
  • Plan to drink alcohol during treatment with LAMPIT

 

Before taking LAMPIT, tell your healthcare provider about all your medical conditions, including if you:

  • have a history of brain injury, seizures, mental health problems or behavioral changes.
  • have kidney problems or are on dialysis.
  • have liver problems.
  • have a genetic problem called porphyria. Taking LAMPIT can make your symptoms of porphyria including dark urine, severe stomach pain, muscle pain, tingling, numbness, mental changes or skin sensitivity to light worse.
  • are pregnant, plan to become pregnant, or think you may be pregnant. LAMPIT can harm your unborn baby.

 For females who are able to become pregnant:

  • Your healthcare provider should do a pregnancy test before you start taking LAMPIT to make sure that you are not pregnant.
  • You should use effective forms of birth control during treatment with LAMPIT and for 6 months after your last dose of LAMPIT. Talk to your healthcare provider about what forms of birth control may be right for you.
  • Call your healthcare provider right away if you become pregnant or think you are pregnant during treatment with LAMPIT.

For males:

  • LAMPIT may cause fertility problems in males. This may affect your ability to father a child. Talk to your healthcare provider if you have concerns about fertility.
  • You should use a condom with female partners who are able to become pregnant, during treatment with LAMPIT and for 3 months after your last dose of LAMPIT.
  • are breastfeeding or plan to breastfeed. LAMPIT can pass into breast milk and may harm your baby. Talk to your healthcare provider about the best way to feed your baby during treatment with LAMPIT. If you take LAMPIT and breastfeed, monitor your baby for vomiting, rash, decreased appetite, fever, and irritability.

 

Tell your healthcare provider about all the medicines you take, including prescription and over-the-counter medicines, vitamins, and herbal supplements.

 

What are the possible side effects of LAMPIT?

 

LAMPIT may cause serious side effects, including:

  • Worsening of symptoms related to brain injury, seizures, mental health problems or behavior changes in people with a history of these problems. Call your healthcare provider right away if any of these problems get worse during treatment with LAMPIT.
  • Allergic reactions. Allergic reactions can happen when taking nifurtimox, the active ingredient in LAMPIT, or with changes in your immune system caused by Chagas disease during treatment with LAMPIT. These allergic reactions can include low blood pressure, swelling of the face and tongue (angioedema), shortness of breath, itching, rash or other skin problems. Call your healthcare provider or get emergency medical help if you get any of these signs and symptoms of an allergic reaction during treatment with LAMPIT.
  • Loss of appetite and weight loss. Your healthcare provider should check your weight every 14 days to see if your dose of LAMPIT may need to be changed.

 

The most common side effects of LAMPIT include: vomiting, abdominal pain, headache, decreased appetite, nausea, fever, and rash.

 

These are not all the possible side effects of LAMPIT. Tell your healthcare provider if you have any side effect that bothers you or that does not go away.

 

Please see the full Prescribing Information for additional information.

You are encouraged to report side effects or quality complaints of products to the FDA by visiting www.fda.gov/medwatch or calling 1‑800‑FDA‑1088.

 

For Bayer products, you can report these directly to Bayer by clicking here. 

 

BAYER, the Bayer Cross, and LAMPIT are registered trademarks of Bayer. 

 

All other trademarks are the property of their respective owners.

 

© 2023 Bayer. All rights reserved. 

 

Site Last Modified 06/2023

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